Synthesis of Carbon Quantum Dots (CQDs) from White Turmeric Doped with DMF as an Antioxidant

Hestina; Yosi Cinthya  Eriwati; Liver Iman Putra Zai; Langsar  Bawamenewi

doi:10.35472/jsat.v10i1.2519

Hestina Universitas Sari Mutiara Indonesia
Yosi Cinthya Eriwati Universitas Sari Mutiara Indonesia
Liver Iman Putra Zai Universitas Sari Mutiara Indonesia
Langsar Bawamenewi Universitas Sari Mutiara Indonesia

DOI: https://doi.org/10.35472/jsat.v10i1.2519

Keywords: nanotechnology, hydrothermal, optical optic, IC50, Curcuma Zedoaria

Abstract

Carbon quantum dots (CQDs) are carbon-based nanomaterials with excellent optical properties and biocompatibility, making them highly promising for applications in bioimaging, biosensing, and antioxidant therapy. This study aims to synthesize CQDs from white turmeric (Curcuma zedoaria) as a natural carbon precursor and to enhance their antioxidant activity through doping with dimethylformamide (DMF). The synthesis was carried out using a hydrothermal method at 180 ℃ for 4 h, followed by purification and characterization using FT-IR, UV-Vis, and photoluminescence (PL) analysis. Antioxidant activity was tested using DPPH and calculated the percentage of scavenging activity (%). FT-IR results confirmed the presence of functional groups such as -OH, C=O, C-N, and -NH, indicating hydrophilic characteristics and active surface functionalities of the CQDs. The UV-Vis spectrum showed an absorption peak at 263 nm corresponding to n–π* and π–π* transitions, while the PL spectrum exhibited fluorescence emission at 449 nm. Antioxidant activity evaluated using the DPPH method demonstrated that white turmeric had 0,13% and CQDs had 5,03%. Overall, the findings indicated that white turmeric can serve as an environmentally friendly carbon source for CQDs synthesis. This study highlights the potential application of turmeric-derived CQDs in bioimaging and delivery.

Downloads

Download data is not yet available.

References

P. K. Yadav, S. Chandra, V. Kumar, S. H. Hasan, “Carbon quantum dots: Synthesis, structure, properties, and catalytic applications for organic synthesis,” Catalysts, vol. 13 (2), pp. 422, 2023.

X. Wang, Y. Feng, P. Dong, J. Huang, “A mini review on carbon quantum dots: preparation, properties, and electrocatalytic application,” Frontiers in Chemistry, vol. 7, pp. 671, 2019.

N. A. Pechnikova, K. Domvri, K. Pospodis, M. S. Istomina, A. V. Laremenko, A. V. Yaremenko, “Carbon quantum dots in biomedical applications: advances, challenges, and future prospects,” Aggregate, vol. 6 (3), pp. 707, November 2024.

N. Azam, M. N. Ali, T. J. Khan, “Carbon quantum dots for biomedical applications: Review and analysis,” Frontiers in Material, vol. 8, pp. 700403, August 2021.

V. L. John, Y. Nair, T. P. Vinod, “Doping and surface modification of carbon quantum dots for enhanced functionalities and related applications,” vol. 38(1), pp. 2100170, September 2021.

L. Jnaus, J. R. Praglowska, M. Piatkowski, D. Bogdal, “Smart, tunable CQDs with antioxidant properties for biomedical applications-ecofriendly synthesis and characterization,” Molecules, vol. 23(3), pp. 736, 2020.

A. Phaniendra, D. B. Jestadi, L. Periyasamy, “Free radicals: properties, sources, targets, and their implication in various diseases,” Indian Journal of Clinical Biochemistry, vol. 30, pp. 11-26, 2015.

Y. Zhang, P. Li, H. Y. Q. Guo, Q. Xu, W. Su, “Analytical and bioanalytical chemistry,” Analytical and Bioanalytical Chemistry, vol. 415, pp/ 1917-1931, 2023.

J. Akter, M. A. Hossain, K. Takaraa, M. Z. Islam, D. Hou, “ Antioxidant activity of different species and varieties of turmeric (Curcuma spp): Isolation of active compounds,” Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, vol. 215, pp. 9-17, January 2019.

V. Dutta, R. Verma, C. Gopalkhrishnan, M. Yuan, K. M. Batoo, R. Jayavel, A. Chaunhan, K. A. Lin, R. Balasubramani, S. Ghotekar, “Bio-inspired synthesis of carbon-based nanomaterials and their potential environmental applications: A state-of-the-art review,” vol. 10 (10), pp. 169, September 2022.

S. Gulati, A. Baul, A. Amar, R. Wadhwa, S. Kumar, R. S. Varma, “Eco-friendly and sustainable pathways to photoluminescent carbon quantum dots (CQDs),” Nanomaterials, vol. 13 (3), pp. 554, 2023.

Hestina, E. Gultom, I. Waruwu, “Pembuatan dan karakterisasi carbon dots dari tanaman kunyit putih dengan metode hidrotermal,” Journal of Chemistry, Education, and Science, vol. 7 (1), June 2023.

Z. Li, Y. Jiang, Y. Li, H. Zhang, H. Li, S. Yang, “Advances in diels-alder/aromatizationof biomass furan derivatives towards renewable aromatic hydrocarbons,” Catalysis Science & Technology, vol. 12, pp. 1902-1921, 2022.

A. Kasouni, T. Chatzimitakos, C. Stalikas, “Bioimaging applications of carbon nanodots: a review,” Recent Advances in Carbon Dots, vol. 5, pp.19, April 2019. 7

F. Wen, P. Li, Y. Zhang, H. Zhong, H. Yan, W. Su, “Preparation, characterization of green tea carbon quantum dots/curcumin antioxidant and antibacterial nanocomposites,” Journal of Molecular Structure, vol. 1273, pp. 134247, February 2023.

L. A. Avinash, A. Kurdekar, S. Patnaik, B. V. Dev, T. M. Rattan, V. Kamisetti, “Carbon quantum dots from coconut husk: Evaluation for antioxidant and cytotoxic activity,” Materials Focus, vol. 5, pp. 55-61, 2016.

H. Crenata, “Antioxidant capacity and biological activity of essential oil and methanol extract of hyptis crenata,” Rev. Bras. Farmacogn, vol. 19 (1B), 2009.

C. Shen, H. Jun, Y. Kim, E. Jung, G. Oh, S. Joo, S. Kim, I. Kim, “Evaluation of antioxidant activities and active compounds separated from water soluble extracts of Korean black pine barks,” Bull. Korean Chem. Soc, vol. 31, pp. 3567, 2010.